Maternal Maternal B Risk and Screening Suggestions

B Streptococcus (GBS) is a conditional pathogenic bacteria that can be interrupted, excessive or persistently planted in digestive tract and reproductive tract.

1. The risk of GBS infection to maternal and infants

1. Maternal maternal infection

GBS planted in pregnant women can cause disease under certain conditions, causing pregnant women to have asymptomatic bacteria, cystitis, pyelonephritis, bacteria, amniocemic cavity, pneumonia, premature birth, postpartum endometritis and postpartum purulent disease, etc.And death in the fetus.The incidence of postpartum endometritis and sepsis caused by GBS in the United States is 0.1%and 0.2%; newborn GBS infection rates are 0.1%and 0.2%, and the mortality rate is 5%.

2. Newborn infection

After the mother passes GBS to the newborn, it can lead to the infection of sepsis and central nervous system in the child. In severe cases, even death can cause the sequelae of the nervous system due to inflammatory damage.The incidence of pneumonia and upper respiratory tract infections of GBS -positive women in my country is 11.0%and 8.3%, which is higher than 9.7%and 6.1%higher than negatives. %And 10.0%are also higher than 14.9%and 5.0%of the negatives.

2. The fixed rate of gBS of pregnant women: In 2017, 390 studies in 85 countries 299924 pregnant women conducted a systematic evaluation, showing that the overall pregnant women’s GBS planting rate was 18%, South Asia is 12.5%, and East Asia is 11%; my country: From 2000 to 2018, 30 studies were published in 44716 pregnant women’s META analysis, and the GBS planting rate of pregnant women in China was 11.3%.

3. GBS screening and prevention scheme during pregnancy

1. GBS screening for all pregnant women who are 35-37 weeks of pregnancy;

2. Those who have GBS urine during pregnancy or those who have a newborn GBS medical history in the past can directly treat GBS positive;

3. Preventive treatment of fever ≥38 ° C, premature birth, premature lunar membrane breakfast, fetal membrane rupture ≥18 h, etc. Preventive treatment;

4. GBS screening is valid for 5 weeks. If GBS negatives have not given birth for more than 5 weeks, repeated screening.

5. The previous pregnancy has a history of GBS planting. After informed the consent, it is experienced for GBS preventive medication.

6. Caesarean section that does not break the membrane and does not enter the production process does not need to use antibiotics for prevention of GBS.

Fourth, drug selection

1. Preferring penicillin;

2. Elerticulfin allergy, choose cephalopiolin;

3. Cobe allergies, use Klimerin according to GBS strain drug sensitivity

4. Kyromycin is not sensitive and uses vancin.

【references】

[1] Zhu Min, Fan Jianxia, Chenglinnan. The research progress of the B-mortar infection of Blore bacteria in the feast period [J]. Chinese Women’s Magazine, 2005, 02: 68-72.

[2] The Medical Branch of the Chinese Medical Association, the China Medical Association’s Obstetrics and Gynecology Branch of the Obstetrics and Gynecology Branch.8): 561-566. Doi: 10.3760/CMA.J.CN113903-20210716-00638.

Baby Scale-(24inch)


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